Have you ever tried an edible only to not feel anything for 20 minutes, so you eat more then BAM. You’re stoned as a rock? Yeah, same. Edibles are notorious for being the strongest method of consuming cannabis, except for probably dabs (of course). So what Makes Edibles So Potent?

Aside from the fact that you can consume a lot more at in one sitting, something else happens when you eat cannabis:

A competently different cannabinoid is formed – 11-hydroxy-THC.

People claim you can get even more stoned off of a half of a gram if you orally consume cannabis than if you blaze it; it really depends on each persons preferences. Some people relate this to the concept that from oral consumption “your body digests and absorbs all the THC,” whereas when you toke up, a lot of THC gets burnt or otherwise destroyed.

It is true that combustion wastes a ton of active cannabinoids, but there is no way that oral ingestion leads you to absorb ALL of the THC. There’s actually even less absorbed than what actually gets into your bloodstream; in fact, according to a National Institutes of Health study, “oral THC bioavailability is only 6% -10%”. Low water-solubility, digestion in the stomach and saliva are the culprits for a lot of the THC passing through your body without you experiencing the high you are looking for. So how the hell does it work? Why do edibles hit you like a MACK truck?

It’s well known fact that THC must be decarbed in order for it to do anything in an edible, but something cool happens metabolically when you eat it that doesn’t happen when you inhale it. Almost half of orally consumed THC gets converted into 11-hydroxy-THC, a potent version of it that has an easier time passing through the blood-brain barrier. When you smoke cannabis or otherwise inhale its vapors, pretty much none of the super potent 11-hydroxy-THC is formed.

So the next time you get beat up by an edible, just remember, it’s not only THC that’s kicking your ass. That extra potency is from some advanced science happening.